Acute lymphoblastic leukaemia: trimethoprim resistant organisms during treatment.

Investigation of TEL/AML1 and BCR/ABL Fusion Genes in Patients Affected by Acute Lymphoblastic Leukaemia Using Interphase in situ Hybridization

Gene variants of CYP1A1 and CYP2D6 and the risk of childhood acute lymphoblastic leukaemia; outcome of a case control study from Kashmir, India

Studies on associations of various polymorphisms in xenobiotic metabolizing genes with different cancers including acute lymphoblastic leukaemia (ALL) are mixed and inconclusive. The current study analyzed the relationship between polymorphisms of phase I xenobiotic metabolizing enzymes, cytochromes P450 1A1 (CYP1A1) and CYP2D6 and childhood ALL in Kashmir, India. We recruited 200 confirmed ALL...

Long-term results of national treatment trials in childhood acute lymphoblastic leukaemia in several Middle/East European countries

Acute lymphoblastic leukaemia (ALL) is the most frequent childhood cancer. During the last 50 years its prognosis has improved from zero probability of survival in the 1950s to more than 80% chance to be cured at the beginning of the 21st century. ALL is a highly chemosensitive disease and its successful treatment is a good indicator of the level of medical care that children with cancer get in...

Mycotic intracranial abscesses during induction treatment for acute lymphoblastic leukaemia.

A boy with newly diagnosed acute lymphoblastic leukaemia developed mycotic cerebral abscesses despite treatment with amphotericin. He survived this episode on combination antifungal treatment.

Haemophagocytic syndrome complicating acute lymphoblastic leukaemia.

A 41 year old female developed reactive haemophagocytic histiocytosis secondary to herpes simplex infection, during remission induction for acute lymphoblastic leukaemia. She recovered fully with acyclovir and supportive treatment. Previous publications on the association between acute lymphoblastic leukaemia and haemophagocytic syndrome are reviewed, and the nature of the haemophagocytic disor...